Faster DNA Synthesis without Hazardous Waste
There has been an exciting molecular biology method development reported in Nature Biotechnology! DNA is normally synthesized through the nucleoside phosphoramidite method that was first published in 1981. Joint Bioenergy Institute (JBEI) researchers and their collaborators have demonstrated proof of concept for a new enzymatic based method that has many advantages. The new method increases the speed off DNA synthesis. It removes the need for solvent use, which is a hazardous waste. Overall it will drop the cost of synthesizing DNA. It's terrific work, and an advance that we at Labconscious applaud as a greener biochemistry method for life science laboratory work.
Watch the JBEI video below, read the full story on the JBEI website here, and review all the technical details in the report De novo DNA Synthesis Using Polymerase-Nucleotide Conjugates (2018) Nature Biotechnology.